⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306264 | 0.76 | ALDH1A1 (0.44) | — | |
| SCHEMBL1044593 | 0.76 | ALDH1A1 (0.44) | — | |
| N-Methyl-N-Nitrosurea SCHEMBL18660152 | 0.71 | FFAR3 (0.37) | — | |
| SCHEMBL250406 | 0.71 | — | — | |
| SCHEMBL30881951 | 0.71 | — | — | |
| SCHEMBL3500103 | 0.71 | — | — | |
| N-Methyl-N-Nitrosurea SCHEMBL28025247 | 0.71 | ALDH1A1 (0.39) | — | |
| N-Methyl-N-Nitrosurea SCHEMBL38377 | 0.71 | — | — | |
| N-Nitrosodimethylamine SCHEMBL28300409 | 0.70 | — | — | |
| N-Methyl-N-Nitrosurea SCHEMBL27465067 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234918-A1 | AUTOMATED DIAZOMETHANE GENERATOR, REACTOR AND SOLID PHASE QUENCHER | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-07-27 | — | — | US | claimed |
| CN-115956066-A | Automatic diazomethane generator, reactor and solid phase quenching agent | 科学与工业研究委员会 | 2023-04-11 | — | — | CN | claimed |
| US-9233924-B2 | Methods for preparing D-threo methylphenidate using diazomethane, and compositions thereof | AMPAC FINE CHEMICALS LLC (US) | 2016-01-12 | — | — | US | claimed |
| US-20150259289-A1 | METHODS FOR PREPARING D-THREO METHYLPHENIDATE USING DIAZOMETHANE, AND COMPOSITIONS THEREOF | AMPAC FINE CHEMICALS LLC (US) | 2015-09-17 | — | — | US | claimed |
| EP-0916649-B1 | Large scale batch process for diazomethane | AEROJET FINE CHEMICALS LLC (US) | 2002-01-23 | — | — | EP | claimed |
| EP-0916649-A1 | Large scale batch process for diazomethane | AEROJET-GENERAL CORPORATION (US) | 1999-05-19 | — | — | EP | claimed |
| US-5817778-A | FROM AN N-METHYL-N-NITROSOAMINE, PHASE TRANSFER CATALYST | AEROJET-GENERAL CORPORATION (US) | 1998-10-06 | — | — | US | claimed |
| CN-115867129-B | Resistance of tomato plants to ToBRFV | 维尔莫林公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119173539-A | Multispecific constructs and uses thereof | 天境生物科技(上海)有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118843468-A | Use of hyaluronic acid-nimesulide complexes for the treatment of local late or metastatic tumors | 爱禾公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-115811936-B | Melon plants resistant to scab, aphid and powdery mildew | 维尔莫林公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117205152-B | Pharmaceutical carrier, preparation method thereof and application thereof in disease treatment | 南京大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117205152-A | Pharmaceutical carrier, preparation method thereof and application thereof in disease treatment | 南京大学 | 2023-12-12 | — | — | CN | disclosed |
| EP-0916648-A1 | Continuous process for diazomethane | AEROJET-GENERAL CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0916649-A1 | Large scale batch process for diazomethane | AEROJET-GENERAL CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5854405-A | Continuous process for diazomethane from an n-methyl-n-nitrosoamine and from methylurea through n-methyl-n-nitrosourea | AEROJET-GENERAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5817778-A | FROM AN N-METHYL-N-NITROSOAMINE, PHASE TRANSFER CATALYST | AEROJET-GENERAL CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0117797-A1 | Nitroso ureas, process for their preparation and their therapeutic use | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-09-05 | — | — | EP | disclosed |
| WO-1984003088-A1 | NEW NITROSOUREAS, PREPARATION METHOD THEREOF AND THEIR APPLICATION IN THERAPY | CENTRE NAT RECH SCIENT (FR) | 1984-08-16 | — | — | WO | disclosed |
| US-4407739-A | OXIDATION RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |