⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044593 | 0.87 | ALDH1A1 (0.44) | — | |
| SCHEMBL11306264 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL20849730 | 0.73 | — | — | |
| SCHEMBL18472274 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL6523333 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL24760 | 0.71 | — | — | |
| SCHEMBL136249 | 0.71 | — | — | |
| SCHEMBL103330 | 0.71 | — | — | |
| SCHEMBL437868 | 0.71 | TSHR (0.35) | — | |
| N-Methyl-N-Nitrosurea SCHEMBL38377 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184033-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | Lineage Cell Therapeutics, Inc. | 2010-07-22 | — | — | US | disclosed |
| US-20080226601-A1 | Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods | UNIVERSITY OF ROCHESTER (US) | 2008-09-18 | — | — | US | disclosed |
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| US-5366900-A | Exposing to ultraviolet radiation to make nitric oxide; detection | CORNELL RESEARCH FOUNDATION, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5094815-A | Chromatography, formation and detection of nitric oxide | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-03-10 | — | — | US | disclosed |