Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.47 |
| ▸ | CTSL | P07711 | 6/20 | 0.35 |
| ▸ | CTSB | P07858 | 5/20 | 0.35 |
| ▸ | CTSH | P09668 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725733 | 0.87 | CTSK (0.51) | CTSKCTSLCTSBCTSH | |
| SCHEMBL25710428 | 0.82 | CTSK (0.46) | CTSKCTSLCTSBCTSHTAS1R3 | |
| SCHEMBL27656524 | 0.79 | FAAH (0.55) | CTSK | |
| SCHEMBL56438 | 0.79 | CTSK (0.50) | CTSKCTSLCTSBCTSHTAS1R3 | |
| SCHEMBL4786392 | 0.79 | CTSK (0.50) | CTSKCTSLCTSBCTSHTAS1R3 | |
| SCHEMBL328961 | 0.79 | CTSK (0.50) | CTSKCTSLCTSBCTSHTAS1R3 | |
| SCHEMBL27656727 | 0.79 | MEN1 (0.46) | CTSK | |
| SCHEMBL23505641 | 0.78 | FAAH (0.58) | CTSK | |
| SCHEMBL27656564 | 0.78 | FAAH (0.58) | CTSK | |
| SCHEMBL23505651 | 0.78 | FAAH (0.58) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138511-A1 | LONG-ACTING Y2 AND/OR Y4 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2009-11-19 | — | — | WO | disclosed |