Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.42 |
| ▸ | CTSB | P07858 | 5/20 | 0.42 |
| ▸ | CTSH | P09668 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15060848 | 0.87 | CTSK (0.53) | CTSKCTSLCTSBCTSH | |
| SCHEMBL13624945 | 0.87 | CTSK (0.47) | CTSKCTSLCTSBCTSH | |
| SCHEMBL16478000 | 0.81 | CTSK (0.54) | CTSKCTSLCTSBCTSH | |
| SCHEMBL27656524 | 0.79 | FAAH (0.55) | CTSKMEN1KMT2AASAH1DEGS1 | |
| SCHEMBL5879115 | 0.78 | SLC6A5 (0.59) | CTSKMEN1KMT2AASAH1DEGS1 | |
| SCHEMBL12446457 | 0.78 | SLC6A5 (0.59) | CTSKMEN1KMT2AASAH1DEGS1 | |
| SCHEMBL23505641 | 0.77 | FAAH (0.58) | CTSKMEN1KMT2AASAH1DEGS1 | |
| SCHEMBL27656564 | 0.77 | FAAH (0.58) | CTSKMEN1KMT2AASAH1DEGS1 | |
| SCHEMBL27656694 | 0.77 | FAAH (0.58) | CTSKMEN1KMT2AASAH1DEGS1 | |
| SCHEMBL23505651 | 0.77 | FAAH (0.58) | CTSKMEN1KMT2AASAH1DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832898-A2 | Substituted amino acid derivatives | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |