Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 13/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625206 | 0.92 | EPHX1 (0.50) | EPHX1HRH4HRH3NAAAASAH1 | |
| SCHEMBL7897305 | 0.75 | ACHE (0.46) | EPHX1 | |
| SCHEMBL13625208 | 0.73 | ACHE (0.39) | — | |
| SCHEMBL7897322 | 0.72 | CYP2C9 (0.39) | EPHX1 | |
| SCHEMBL13619348 | 0.72 | EPHX1 (0.48) | EPHX1HRH4HRH3NAAAASAH1 | |
| SCHEMBL13625209 | 0.70 | MEN1 (0.38) | — | |
| SCHEMBL13966780 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL5942748 | 0.69 | EPHX1 (0.50) | EPHX1 | |
| SCHEMBL17342594 | 0.69 | EPHX1 (0.48) | EPHX1HRH4HRH3NAAAASAH1 | |
| SCHEMBL13625210 | 0.69 | SMN1; SMN2 (0.52) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |