Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897305 | 0.85 | ACHE (0.46) | ACHEMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7897322 | 0.76 | CYP2C9 (0.39) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16298775 | 0.72 | ACHE (0.53) | ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL16298774 | 0.72 | ACHE (0.53) | ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL20089025 | 0.71 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL13625206 | 0.71 | EPHX1 (0.50) | — | |
| SCHEMBL10106984 | 0.69 | CYP2C9 (0.49) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL13625209 | 0.69 | MEN1 (0.38) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2819850 | 0.69 | ACHE (0.47) | ACHEALDH1A1 | |
| SCHEMBL17208303 | 0.68 | ACHE (0.48) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |