Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944652 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8394496 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8396686 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL7905615 | 0.77 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1 | |
| SCHEMBL8392063 | 0.77 | NPC1 (0.55) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8395708 | 0.77 | NPC1 (0.55) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL4920810 | 0.77 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL27493272 | 0.76 | NAAA (0.55) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL28866304 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL28255730 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RECQLRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |