Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124636 | 1.00 | ACHE (0.48) | ACHEEGLN1EPHX2 | |
| SCHEMBL12933052 | 0.93 | ACHE (0.51) | ACHEEPHX2 | |
| SCHEMBL13153845 | 0.88 | ACHE (0.50) | ACHEEGLN1EPHX2 | |
| SCHEMBL16298774 | 0.82 | ACHE (0.53) | ACHE | |
| SCHEMBL16298775 | 0.82 | ACHE (0.53) | ACHE | |
| SCHEMBL461365 | 0.81 | ACHE (0.58) | ACHEEPHX2 | |
| SCHEMBL12962554 | 0.80 | ACHE (0.43) | ACHEEGLN1EPHX2 | |
| Hydrochloric Acid SCHEMBL2185194 | 0.79 | ACHE (0.56) | ACHEEPHX2 | |
| SCHEMBL8849277 | 0.79 | ACHE (0.61) | ACHEEPHX2 | |
| SCHEMBL13416641 | 0.79 | ACHE (0.34) | ACHEEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150306241-A1 | COPOLYMERS FOR THE DELIVERY OF DRUGS INTO CELLS | NORTHEASTERN UNIVERSITY | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306241-A1 | COPOLYMERS FOR THE DELIVERY OF DRUGS INTO CELLS | MMP9, MMP2, MMP26 | ACHE 2014/4885EGLN1 1591/4885EPHX2 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.