Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27493272 | 0.96 | NAAA (0.55) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8394496 | 0.94 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8396686 | 0.94 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8392063 | 0.93 | NPC1 (0.55) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8395708 | 0.93 | NPC1 (0.55) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8396273 | 0.91 | GRIN2B (0.50) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8393228 | 0.86 | HRH4 (0.58) | SMN1; SMN2NPC1RECQLRAB9ALMNA | |
| SCHEMBL8944752 | 0.86 | EPHX2 (0.51) | SMN1; SMN2NPC1RECQLRAB9AALDH1A1 | |
| SCHEMBL8392576 | 0.86 | GRIN2B (0.48) | SMN1; SMN2NPC1RECQLRAB9AALDH1A1 | |
| SCHEMBL8397655 | 0.85 | RAB9A (0.55) | SMN1; SMN2NPC1RECQLRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |