SCHEMBL7739770

SCHEMBL7739770

CC1CCC(C)(C)C(O)C1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.32
TRPM8 Q7Z2W7 2/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793502 0.78 PTPN2 (0.33) TRPA1TRPM8
SCHEMBL26088608 0.78
SCHEMBL13625216 0.78
SCHEMBL5868448 0.77 LMNA (0.39) CYP3A4
SCHEMBL15127464 0.76 TRPA1 (0.30) TRPA1TRPM8
Hydrochloric Acid SCHEMBL28115986 0.75
SCHEMBL24685640 0.74
SCHEMBL19321814 0.73 CYP3A4 (0.31) CYP3A4
SCHEMBL23196708 0.73 TRPA1 (0.36) TRPA1TRPM8
SCHEMBL12166816 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593077-B1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2016-11-02 EP disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 US disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 US disclosed
WO-2014121037-A1 HYDROXYLAMINE-TERMINATED POLYSILOXANE AND METHODS OF MAKING AND USING THE SAME DOW CORNING CORPORATION (US) 2014-08-07 WO disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 US disclosed
EP-0144712-B1 OPTICAL FIBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-30 EP disclosed
US-4717756-A HYDROPEROXIDE INITIATOR, SULFUR REDUCTANT, HYDROGEN HALOGENIDE SALT, COPPER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-01-05 US disclosed
EP-0231395-A1 PROCESS FOR PRODUCING METHACRYLATE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-12 EP disclosed
EP-0217545-A1 Method for the production of polymethacrylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-04-08 EP disclosed
EP-0190656-A2 Method for producing plastic optical fiber with heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-13 EP disclosed
US-4576438-A Heat-resisting optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-18 US disclosed
EP-0162472-A2 Plastic optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-27 EP disclosed
EP-0154339-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-11 EP disclosed
EP-0144712-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-19 EP disclosed
EP-0097325-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES CBR1, CYP2A13, CBR3 TRPA1 304/4885TRPM8 1735/4885CYP3A4 39/4885
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS CBR1, NCOR2, CECR2 TRPA1 462/4885TRPM8 2152/4885CYP3A4 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.