Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20729409 | 0.88 | DNM1 (0.45) | LMNALPAR1LPAR3LPAR6LPAR4 | |
| SCHEMBL4925955 | 0.86 | CNR2 (0.56) | LMNAALDH1A1CNR1CNR2LPAR1 | |
| SCHEMBL5831760 | 0.86 | LMNA (0.50) | LMNAALDH1A1CNR1CNR2MAPT | |
| SCHEMBL3391670 | 0.86 | CNR2 (0.56) | LMNAALDH1A1CNR1CNR2LPAR1 | |
| SCHEMBL17817321 | 0.86 | CNR2 (0.51) | LMNAALDH1A1CNR1CNR2LPAR1 | |
| SCHEMBL9329951 | 0.86 | CNR2 (0.56) | LMNAALDH1A1CNR1CNR2LPAR1 | |
| SCHEMBL10520454 | 0.86 | CNR2 (0.56) | LMNAALDH1A1CNR1CNR2LPAR1 | |
| SCHEMBL7800390 | 0.86 | CNR2 (0.56) | LMNAALDH1A1CNR1CNR2LPAR1 | |
| SCHEMBL11300731 | 0.86 | CNR2 (0.56) | LMNAALDH1A1CNR1CNR2LPAR1 | |
| SCHEMBL7191931 | 0.86 | CNR2 (0.51) | LMNAALDH1A1CNR1CNR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067398-B2 | Biodegradable polymers having a pre-determined chirality | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2011-11-29 | — | — | US | disclosed |
| US-20090318339-A1 | Biodegradable polymers having a pre-determined chirality | Yissum Research Development Company of The Hebrew Univerisity of Jerusalem (IL) | 2009-12-24 | — | — | US | disclosed |
| EP-1902084-A2 | BIODEGRADABLE POLYMERS HAVING A PRE-DETERMINED CHIRALITY | Yissum Research Development Company, of The Hebrew University of Jerusalem (IL) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006129320-A2 | BIODEGRADABLE POLYMERS HAVING A PRE-DETERMINED CHIRALITY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318339-A1 | Biodegradable polymers having a pre-determined chirality | PAICS, CD14, PCNA | LMNA 23/4885ALDH1A1 1607/4885CNR1 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.