Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831665 | 0.80 | CA12 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL1754885 | 0.80 | APP (0.74) | APPNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL29203828 | 0.76 | MAOA (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8909968 | 0.74 | GRM5 (0.65) | APPMAPTGRM5CA12CA1 | |
| SCHEMBL106193 | 0.73 | — | — | |
| SCHEMBL17781322 | 0.72 | CASP3 (0.45) | S100A4CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL2015334 | 0.71 | APP (0.55) | APPALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL17113634 | 0.71 | NPC1 (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL30350052 | 0.69 | NPC1 (0.77) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL864582 | 0.69 | NPC1 (0.77) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619265-B2 | Molecular single electron transistor (MSET) detector device | QINETIQ LIMITED (GB) | 2009-11-17 | — | — | US | disclosed |
| US-20070134667-A1 | Molecular single electron transistor (mset) detector device | QINETIO LIMITED (GB) | 2007-06-14 | — | — | US | disclosed |