Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297018 | 0.88 | POLB (0.67) | POLBMAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL23615473 | 0.87 | HDAC3 (0.58) | POLBMAPTNPC1SMN1; SMN2HDAC3 | |
| SCHEMBL14297019 | 0.85 | POLB (0.49) | POLBMAPTNPC1SMN1; SMN2HTR2A | |
| SCHEMBL20054903 | 0.85 | POLB (0.46) | POLBMAPTNPC1SMN1; SMN2HDAC3 | |
| SCHEMBL14297023 | 0.83 | ALDH1A1 (0.57) | POLBMAPTNPC1SMN1; SMN2HDAC3 | |
| SCHEMBL13880959 | 0.83 | POLB (0.46) | POLBMAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL4400681 | 0.83 | POLB (0.46) | POLBMAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL20196333 | 0.82 | POLB (0.45) | POLBMAPTNPC1SMN1; SMN2GAA | |
| SCHEMBL13643864 | 0.82 | POLB (0.47) | POLBMAPTNPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL13625469 | 0.82 | POLB (0.45) | POLBMAPTNPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |