Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983820 | 0.81 | HPGDS (0.43) | LTA4HCHRNA7CHRNA10CHRNA9HPGDS | |
| SCHEMBL8239613 | 0.80 | LTA4H (0.50) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL722557 | 0.79 | LTA4H (0.64) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL17254244 | 0.77 | KCNJ1 (0.49) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL28257875 | 0.77 | LTA4H (0.62) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL28362996 | 0.77 | LTA4H (0.62) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL28320605 | 0.77 | LTA4H (0.62) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL3373791 | 0.77 | LTA4H (0.50) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL9263374 | 0.77 | NOTUM (0.53) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 | |
| SCHEMBL15018654 | 0.77 | LTA4H (0.50) | LTA4HCHRNA7CHRNA10CHRNA9KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622452-B2 | C-9 alkenylidine bridged macrolides | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080119418-A1 | C-9 ALKENYLIDINE BRIDGED MACROLIDES | ENANTA PHARMACEUTICALS, INC. | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119418-A1 | C-9 ALKENYLIDINE BRIDGED MACROLIDES | CYP2C9, CCR9, DPP9 | LTA4H 415/4885CHRNA7 4617/4885CHRNA10 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.