Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625663 | 0.80 | LMNA (0.49) | NPC1ALDH1A1LMNAHPGDTAAR1 | |
| SCHEMBL988376 | 0.78 | TAAR1 (0.53) | NPC1ALDH1A1LMNAHPGDTAAR1 | |
| SCHEMBL27893993 | 0.78 | HPGD (0.49) | NPC1ALDH1A1HPGDTAAR1MAPT | |
| SCHEMBL11615931 | 0.77 | TAAR1 (0.51) | NPC1ALDH1A1LMNAHPGDTAAR1 | |
| SCHEMBL13374714 | 0.75 | HPGD (0.47) | NPC1ALDH1A1HPGDTAAR1MAPT | |
| SCHEMBL2220979 | 0.75 | ALDH1A1 (0.49) | NPC1ALDH1A1LMNAHPGDTAAR1 | |
| SCHEMBL3944420 | 0.75 | HPGD (0.47) | NPC1ALDH1A1HPGDTAAR1MAPT | |
| SCHEMBL4422302 | 0.73 | NPC1 (0.46) | NPC1TDP1NAAAATM | |
| SCHEMBL10448778 | 0.72 | SMN1; SMN2 (0.46) | NPC1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL9623345 | 0.72 | HPGD (0.46) | NPC1ALDH1A1LMNAHPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |