Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625647 | 0.80 | NPC1 (0.46) | LMNAALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL27893993 | 0.75 | HPGD (0.49) | ALDH1A1MAPTHTTHSD17B10NPSR1 | |
| SCHEMBL988376 | 0.75 | TAAR1 (0.53) | LMNAALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL11615931 | 0.73 | TAAR1 (0.51) | LMNAALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL3944420 | 0.72 | HPGD (0.47) | ALDH1A1MAPTHTTHSD17B10NPSR1 | |
| SCHEMBL2220979 | 0.72 | ALDH1A1 (0.49) | LMNAALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL13374714 | 0.72 | HPGD (0.47) | ALDH1A1MAPTHTTHSD17B10NPSR1 | |
| SCHEMBL2722040 | 0.71 | LMNA (0.46) | LMNAMAPTNPC1RAB9ATSHR | |
| SCHEMBL12735068 | 0.71 | NAAA (0.52) | LMNAALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL4404820 | 0.70 | NPC1 (0.58) | LMNAMAPTPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |