Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 10/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 10/20 | 0.35 |
| ▸ | PRKCG | P05129 | 7/20 | 0.35 |
| ▸ | PRKCB | P05771 | 7/20 | 0.35 |
| ▸ | PRKCH | P24723 | 7/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 4/20 | 0.31 |
| ▸ | PRKACG | P22612 | 3/20 | 0.31 |
| ▸ | PRKACB | P22694 | 3/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625650 | 0.72 | SERPINE1 (0.49) | SERPINE1PRKCAPRKCDALDH1A1MEN1 | |
| SCHEMBL13625652 | 0.71 | SERPINE1 (0.44) | SERPINE1PRKCAPRKCDMEN1KMT2A | |
| SCHEMBL4312250 | 0.70 | PRKCA (0.45) | PRKCAPRKCDALDH1A1KMT2ACREBBP | |
| SCHEMBL28837883 | 0.69 | CYP1A2 (0.40) | SERPINE1PRKCAPRKCDPRKCGPRKCB | |
| SCHEMBL1551997 | 0.69 | TPMT (0.50) | PRKCAPRKCDALDH1A1CREBBP | |
| SCHEMBL27653743 | 0.68 | SERPINE1 (0.55) | SERPINE1MEN1KMT2A | |
| SCHEMBL7181835 | 0.68 | NPC1 (0.33) | SERPINE1ALDH1A1MEN1KMT2A | |
| SCHEMBL475791 | 0.67 | SLC7A5 (0.49) | PRKCAPRKCDALDH1A1CREBBP | |
| SCHEMBL2611728 | 0.67 | SERPINE1 (0.53) | SERPINE1ALDH1A1MEN1KMT2A | |
| SCHEMBL7054328 | 0.67 | SERPINE1 (0.53) | SERPINE1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |