Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.62 |
| ▸ | MLYCD | O95822 | 2/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625756 | 0.92 | MEN1 (0.72) | PRKCAPRKCDMEN1KMT2APLA2G1B | |
| SCHEMBL15847083 | 0.86 | MLYCD (0.62) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL26508192 | 0.83 | MEN1 (0.63) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL23978883 | 0.82 | MEN1 (0.69) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL13626187 | 0.79 | MEN1 (0.48) | PRKCAPRKCDMEN1KMT2APLA2G1B | |
| SCHEMBL5227678 | 0.79 | MLYCD (0.86) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL23447721 | 0.79 | MLYCD (0.77) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL2770270 | 0.79 | NOTUM (0.62) | PRKCAPRKCDGAATDP1LMNA | |
| SCHEMBL26625302 | 0.78 | MLYCD (0.76) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL13625633 | 0.78 | PRKCA (1.00) | PRKCAPRKCDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |