Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 1/20 | 1.00 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP12 | P39900 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879196 | 0.82 | PRKCA (0.70) | PRKCAPRKCDMMP1MMP12NR4A2 | |
| SCHEMBL13625639 | 0.82 | PRKCA (0.69) | PRKCAPRKCDMMP1MMP12NR4A2 | |
| SCHEMBL4314829 | 0.81 | KMT2A (0.68) | PRKCAPRKCDLMNAMAPTL3MBTL1 | |
| SCHEMBL13625843 | 0.80 | PRKCA (0.67) | PRKCAPRKCDMMP1MMP12NR4A2 | |
| SCHEMBL20830725 | 0.78 | LMNA (0.66) | PRKCAPRKCDMMP1MMP12NR4A2 | |
| SCHEMBL13625699 | 0.78 | PRKCA (0.63) | PRKCAPRKCDLMNA | |
| SCHEMBL9405203 | 0.78 | PRKCA (0.63) | PRKCAPRKCDMMP1MMP12NR4A2 | |
| SCHEMBL2660451 | 0.78 | PRKCA (0.63) | PRKCAPRKCDMMP1MMP12NR4A2 | |
| SCHEMBL27854715 | 0.78 | PRKCA (0.63) | PRKCAPRKCDMMP1MMP12NR4A2 | |
| SCHEMBL13625640 | 0.78 | PRKCA (0.64) | PRKCAPRKCDMMP1MMP12MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |