Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115092 | 0.91 | ALDH1A1 (0.34) | HSD17B10SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL144798 | 0.85 | DRD2 (0.37) | SMN1; SMN2ALDH1A1POLBEPHX1 | |
| SCHEMBL116350 | 0.85 | CHRM2 (0.39) | HSD17B10SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL116242 | 0.85 | CHRM2 (0.39) | HSD17B10SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL21338831 | 0.77 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL21338832 | 0.77 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL22036328 | 0.73 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2HPGDALDH1A1EPHX1 | |
| SCHEMBL116492 | 0.73 | ALDH1A1 (0.37) | HSD17B10SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL20629743 | 0.73 | ALDH1A1 (0.37) | HSD17B10SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL7819626 | 0.73 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2HPGDALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |