⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626689 | 0.83 | — | — | |
| SCHEMBL18267339 | 0.83 | — | — | |
| SCHEMBL21563220 | 0.83 | LGALS8 (0.31) | — | |
| SCHEMBL17058711 | 0.80 | LGALS8 (0.33) | — | |
| SCHEMBL24709746 | 0.80 | LGALS8 (0.33) | — | |
| SCHEMBL23378918 | 0.80 | LGALS8 (0.33) | — | |
| SCHEMBL13864486 | 0.80 | LGALS8 (0.33) | — | |
| SCHEMBL24709744 | 0.80 | LGALS8 (0.33) | — | |
| SCHEMBL26565556 | 0.80 | — | — | |
| SCHEMBL12990383 | 0.79 | LGALS8 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123759-A2 | Stabilized RNAS as transfection controls and silencing reagents | Dharmacon, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |