SCHEMBL21563220

SCHEMBL21563220

B[C@@H]1O[C@H](CO)C(O[Si](C)(C)C(C)(C)C)C1OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 1/20 0.31
▸ AMY2A P04746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12990383 0.94 LGALS8 (0.31) LGALS8AMY2A
SCHEMBL12769537 0.92 L3MBTL1 (0.31) —
SCHEMBL12049857 0.92 L3MBTL1 (0.31) —
SCHEMBL14643902 0.83 — —
SCHEMBL10072846 0.83 — —
SCHEMBL13625826 0.83 — —
SCHEMBL19146269 0.81 — —
SCHEMBL20654927 0.81 — —
SCHEMBL23113791 0.80 L3MBTL1 (0.35) —
SCHEMBL15763702 0.80 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210238594-A1 COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED ALNYLAM PHARMACEUTICALS, INC. (US) 2021-08-05 — — US disclosed
WO-2019217397-A2 COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED ALNYLAM PHARMACEUTICALS, INC. (US) 2019-11-14 — — WO disclosed
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