⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625826 | 0.80 | — | — | |
| SCHEMBL12990383 | 0.79 | LGALS8 (0.31) | — | |
| SCHEMBL21563220 | 0.79 | LGALS8 (0.31) | — | |
| SCHEMBL23113791 | 0.74 | L3MBTL1 (0.35) | — | |
| SCHEMBL6809069 | 0.73 | L3MBTL1 (0.34) | — | |
| SCHEMBL12049857 | 0.73 | L3MBTL1 (0.31) | — | |
| SCHEMBL6809261 | 0.73 | L3MBTL1 (0.34) | — | |
| SCHEMBL12769537 | 0.73 | L3MBTL1 (0.31) | — | |
| SCHEMBL7587420 | 0.73 | L3MBTL1 (0.34) | — | |
| SCHEMBL3903836 | 0.73 | LGALS8 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |