Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311895 | 0.84 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BHRH3LMNA | |
| SCHEMBL2254217 | 0.82 | ADRA1D (0.50) | ADRA1DADRA1AADRA1BHRH3LMNA | |
| SCHEMBL13616479 | 0.77 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BHRH3LMNA | |
| SCHEMBL6100479 | 0.74 | LMNA (0.51) | ADRA1DADRA1AADRA1BHRH3LMNA | |
| SCHEMBL13625846 | 0.73 | SMN1; SMN2 (0.53) | LMNANOTUM | |
| SCHEMBL2121795 | 0.67 | — | — | |
| SCHEMBL19762486 | 0.67 | — | — | |
| SCHEMBL2759543 | 0.67 | — | — | |
| SCHEMBL19762488 | 0.67 | — | — | |
| SCHEMBL15008976 | 0.66 | LMNA (0.49) | HRH3LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137380-A1 | 3-HYDRAZONE PIPERAZINYL RIFAMYCIN DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-12 | — | — | WO | disclosed |