Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553553 | 0.80 | TSHR (0.38) | TSHRCYP2C19POLBATMLMNA | |
| SCHEMBL15026088 | 0.80 | CYP2C19 (0.46) | TSHRCYP2C19POLBATMLMNA | |
| SCHEMBL1362195 | 0.76 | POLB (0.38) | POLBATMPADI4 | |
| SCHEMBL1364096 | 0.75 | POLB (0.41) | TSHRPOLBATMLMNAPADI4 | |
| SCHEMBL13293899 | 0.75 | TSHR (0.35) | TSHRCYP2C19POLBATM | |
| Hydrochloric Acid SCHEMBL3244070 | 0.74 | TSHR (0.34) | TSHRCYP2C19POLBATM | |
| SCHEMBL1362234 | 0.74 | POLB (0.31) | POLB | |
| SCHEMBL1362974 | 0.74 | POLB (0.31) | POLB | |
| SCHEMBL1361379 | 0.74 | CNR1 (0.47) | CYP2C19POLBPADI4 | |
| SCHEMBL1364230 | 0.71 | ALDH1A1 (0.42) | TSHRPOLBATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8066977-B2 | Agent for permanent hair waving containing heterocyclic mercapto compound | SHOWA DENKO K.K. (JP) | 2011-11-29 | — | — | US | disclosed |
| CN-101184528-B | Permanent waving agent containing heterocyclic mercapto compound | SHOWA DENKO KK | 2010-12-29 | — | — | CN | disclosed |
| EP-1883454-B1 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO KK (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | SHOWA DENKO K.K. (JP) | 2009-08-20 | — | — | US | disclosed |
| CN-101184528-A | Permanent waving agent containing heterocyclic mercapto compound | SHOWA DENKO KK (JP) | 2008-05-21 | — | — | CN | disclosed |
| EP-1883454-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | Showa Denko K.K. (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126729-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO K.K. (JP) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | NSD3, WNT3, MSRB3 | TSHR 1561/4885CYP2C19 2484/4885POLB 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.