Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363 | 0.82 | KDM4E (0.44) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL743471 | 0.82 | KDM4E (0.44) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL11289 | 0.82 | KDM4E (0.44) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL557830 | 0.79 | KDM4E (0.50) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL29939288 | 0.79 | KDM4E (0.50) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL9839916 | 0.78 | KMT2A (0.31) | KMT2APOLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL21312156 | 0.76 | KDM4E (0.47) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL28979578 | 0.76 | KDM4E (0.47) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL2303325 | 0.75 | KDM4E (0.50) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL5108 | 0.75 | ALDH1A1 (0.49) | KDM4EKMT2AMEN1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281616-A1 | MORPHINAN COMPOUNDS | CONCERT PHARMACEUTICALS, INC. (US) | 2017-10-05 | — | — | US | disclosed |
| US-8067638-B2 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090233962-A1 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1911751-A1 | AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
| CN-1195734-C | Phthalic acid diamide derivatives, intermediates in the preparation thereof, agricultural/horticultural insecticides, and methods for using the same | NIHON NOHYAKU CO LTD (JP) | 2005-04-06 | — | — | CN | disclosed |
| CN-1360573-A | Phthalic acid diamide derivatives, intermediates in the preparation thereof, agricultural/horticultural insecticides, and methods for using the same | NIHON NOHYAKU CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233962-A1 | Amide derivative and insecticide containing the same | CYP1A1, CYP4B1, CYP2E1 | KDM4E 496/4885KMT2A 271/4885MEN1 4042/4885 |
| US-20170281616-A1 | MORPHINAN COMPOUNDS | OPRL1, OPRM1, OPRK1 | KDM4E 3738/4885KMT2A 1710/4885MEN1 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.