Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626242 | 0.80 | PKM (0.60) | PKMNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL13626244 | 0.78 | PKM (0.41) | PKMALDH1A1LMNASMN1; SMN2THRB | |
| SCHEMBL28693875 | 0.78 | PKM (0.61) | PKMNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL1074374 | 0.77 | PKM (0.40) | PKMALDH1A1LMNASMN1; SMN2THRB | |
| SCHEMBL692918 | 0.76 | CYP1A2 (0.37) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL30380703 | 0.72 | SMN1; SMN2 (0.47) | PKMALDH1A1LMNASMN1; SMN2THRB | |
| SCHEMBL12479809 | 0.67 | HTT (0.55) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13008386 | 0.67 | SMN1; SMN2 (0.44) | PKMALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8921624 | 0.66 | MEN1 (0.40) | ALDH1A1LMNASMN1; SMN2THRBTSHR | |
| SCHEMBL1075846 | 0.65 | MPO (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |