Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626242 | 0.82 | PKM (0.60) | PKMMAPTMEN1KMT2ALMNA | |
| SCHEMBL1074374 | 0.82 | PKM (0.40) | PKMMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13626243 | 0.78 | PKM (0.41) | PKMMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL2953524 | 0.72 | CYP1A2 (0.42) | MAPTCYP1A2ALDH1A1 | |
| SCHEMBL8921624 | 0.70 | MEN1 (0.40) | MAPTMEN1KMT2ACYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL10338723 | 0.69 | MEN1 (0.39) | PKMMAPTMEN1KMT2ALMNA | |
| SCHEMBL12479809 | 0.68 | HTT (0.55) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL13627068 | 0.68 | LMNA (0.37) | PKMMAPTMEN1KMT2ALMNA | |
| SCHEMBL1076637 | 0.68 | ALDH1A1 (0.37) | PKMMAPTMEN1KMT2ALMNA | |
| SCHEMBL5383506 | 0.66 | PKM (0.44) | PKMMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |