Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 3/20 | 0.43 |
| ▸ | TGM2 | P21980 | 3/20 | 0.43 |
| ▸ | TGM1 | P22735 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144612 | 1.00 | MEN1 (0.43) | MEN1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL25319376 | 0.94 | P2RX7 (0.42) | MEN1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL25324270 | 0.94 | P2RX7 (0.42) | MEN1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL26782863 | 0.92 | P2RX7 (0.50) | MEN1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL116293 | 0.85 | LMNA (0.44) | MEN1KMT2AGAAGFERCA1 | |
| SCHEMBL25318676 | 0.84 | CA1 (0.43) | MEN1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL26782871 | 0.84 | P2RX7 (0.49) | MEN1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL140115 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL141501 | 0.81 | ALDH1A1 (0.53) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL17329132 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AF13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |