Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666543 | 0.84 | MEN1 (0.41) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL12674134 | 0.81 | KDM4E (0.40) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7769259 | 0.81 | KMT2A (0.42) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9812553 | 0.75 | ALDH1A1 (0.38) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9812559 | 0.73 | MAPT (0.38) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28968872 | 0.72 | MAPT (0.42) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| Bicarbonate SCHEMBL28968865 | 0.71 | MAPT (0.49) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL27964089 | 0.71 | MAPT (0.44) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL28529969 | 0.71 | KMT2A (0.46) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL9402238 | 0.71 | MAPT (0.44) | KMT2AMEN1MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |