Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626299 | 0.81 | KMT2A (0.41) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL335541 | 0.76 | KMT2A (0.38) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28529969 | 0.74 | KMT2A (0.46) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL9402238 | 0.74 | MAPT (0.44) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL27964089 | 0.74 | MAPT (0.44) | KMT2AMEN1RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL9402285 | 0.73 | MAPT (0.43) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL5041397 | 0.73 | MAPT (0.43) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL21807366 | 0.73 | HDAC3 (0.46) | KMT2ARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL28250865 | 0.73 | HDAC3 (0.46) | KMT2ARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL637383 | 0.72 | MAPT (0.42) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121446-A1 | AMINOACYLASE AND ITS USE IN THE PRODUCTION OF D-AMINOACIDS | Chirotech Technology Limited (GB) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000023598-A1 | AMINOACYLASE AND ITS USE IN THE PRODUCTION OF D-AMINOACIDS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-04-27 | — | — | WO | disclosed |