Sugi Predict

Sugi Predict / Compounds / SCHEMBL136263

SCHEMBL136263

SCHEMBL136263

Cc1ccc([N+](=O)[O-])c(Cl)n1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CTSB P07858 1/20 0.53
▸ CTSH P09668 1/20 0.53
▸ ALDH1A1 P00352 3/20 0.51
▸ TSHR P16473 3/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ MAPK1 P28482 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.42
▸ MERTK Q12866 1/20 0.41
▸ PIN1 Q13526 2/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ LMNA P02545 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ S1PR4 O95977 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30574931 1.00 CTSB (0.53) CTSBCTSHALDH1A1TSHRTDP1
Methylene Chloride SCHEMBL27897833 0.94 CTSB (0.49) CTSBCTSHALDH1A1TSHRTDP1
Formic Acid SCHEMBL28681221 0.91 CTSB (0.50) CTSBCTSHALDH1A1TSHRTDP1
SCHEMBL30810188 0.85 CTSB (0.54) CTSBCTSHALDH1A1TSHRTDP1
SCHEMBL1135629 0.85 CTSB (0.54) CTSBCTSHALDH1A1TSHRTDP1
SCHEMBL6218586 0.82 POLB (0.42) CTSBCTSHALDH1A1TSHRTDP1
SCHEMBL31030182 0.81 TSHR (0.40) CTSBCTSHALDH1A1TSHRTDP1
SCHEMBL29364858 0.81 MAPT (0.50) ALDH1A1TSHRTDP1MAPK1MERTK
SCHEMBL56616 0.81 MAPT (0.50) ALDH1A1TSHRTDP1MAPK1MERTK
SCHEMBL11239468 0.79 ABCG2 (0.41) CTSBCTSHALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003227-B Synthetic method of 2-methyl-8-methoxybenzofuran [2,3-b ] pyridine 新乡市润宇新材料科技有限公司 2022-03-11 — — CN claimed
CN-110003227-A A kind of synthetic method of 2- methyl -8- Methoxvbenzofuran [2,3-b] pyridine 新乡市润宇新材料科技有限公司 2019-07-12 — — CN claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 — — EP disclosed
US-12503477-B2 Colony stimulating factor-1 receptor (CSF-1R) inhibitors GENZYME CORPORATION 2025-12-23 — — US disclosed
EP-4628488-A1 CYCLIN K DEGRADER AND USE THEREOF Adlai Nortye Biopharma Co., Ltd. (CN) 2025-10-08 — — EP disclosed
US-20250257052-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER INC. (US) 2025-08-14 — — US disclosed
US-20250230157-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS RAPPORT THERAPEUTICS, INC. 2025-07-17 — — US disclosed
EP-3938340-B1 HETEROAROMATIC AND HETEROBICYCLIC AROMATIC DERIVATIVES FOR THE TREATMENT OF FERROPTOSIS-RELATED DISORDERS COLLABORATIVE MEDICINAL DEV LLC (US) 2025-07-09 — — EP disclosed
US-12319669-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2025-06-03 — — US disclosed
US-12304908-B2 Azabenzimidazoles and their use as AMPA receptor modulators RAPPORT THERAPEUTICS, INC. (US) 2025-05-20 — — US disclosed
US-20250115600-A1 COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-04-10 — — US disclosed
US-4948800-A MUSCLE RELAXANTS; ANTICONVULSANTS; ANXIOLYTIC AGENTS; 3-HYDROXYALKYL-PYRIDO(4,5-B OR-C)IMIDAZOLE COMPOUNDS A. H. ROBINS COMPANY, INCORPORATED (US) 1990-08-14 — — US disclosed
US-4914109-A ANTICONVULSANTS, ANTIANXIETY AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1990-04-03 — — US disclosed
US-4873251-A MUSCLE RELAXANTS, ANTICONVULSANTS, ANTIANXIETY AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1989-10-10 — — US disclosed
US-4824951-A MUSCLE RELAXANTS, ANTICONVULSANTS, ANXIOLYTIC AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1989-04-25 — — US disclosed
US-4772600-A MUSCLE RELAXANTS, ANTICONVULSANTS, ANXIOLYTIC A. H. ROBINS COMPANY, INC. (US) 1988-09-20 — — US disclosed
EP-0255217-A1 Fused imidazoheterocyclic compounds A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1988-02-03 — — EP disclosed
US-4698430-A ANTIDEPRESSANT A. H. ROBINS COMPANY, INC. (US) 1987-10-06 — — US disclosed
US-4558132-A ANTIDEPRESSANTS A. H. ROBINS COMPANY, INCORPORATED (US) 1985-12-10 — — US disclosed
EP-0099614-A2 Nitro, amino and aroylamino-N-phenylpyridinamines and their use in a process for preparing pyrido(1,4)benzodiazapines A.H. ROBINS COMPANY, INCORPORATED (US) 1984-02-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115600-A1 COVALENT MODIFIERS OF AKT1 AND USES THEREOF AKT1, AKT1S1, AKT2 CTSB 2717/4885CTSH 3644/4885ALDH1A1 4472/4885
US-20250257052-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF GLP1R, GIPR, GPR119 CTSB 2016/4885CTSH 1749/4885ALDH1A1 747/4885
US-12319669-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GPR119 CTSB 2016/4885CTSH 1749/4885ALDH1A1 747/4885
US-12503477-B2 Colony stimulating factor-1 receptor (CSF-1R) inhibitors CSF1R, CSF3R, IL1RN CTSB 239/4885CTSH 1611/4885ALDH1A1 1517/4885
US-12304908-B2 Azabenzimidazoles and their use as AMPA receptor modulators GRIN1, GRIN2B, GRIN3A CTSB 3654/4885CTSH 4705/4885ALDH1A1 721/4885
US-20250230157-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS GRIN1, GRIN2B, GRIN3A CTSB 3636/4885CTSH 4688/4885ALDH1A1 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.