Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MERTK | Q12866 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.49 |
| ▸ | GSR | P00390 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364858 | 1.00 | MAPT (0.50) | MAPTMERTKTXNRD1GSRTDP1 | |
| SCHEMBL29392605 | 0.83 | MERTK (0.51) | MAPTMERTKTXNRD1GSRTDP1 | |
| SCHEMBL381701 | 0.83 | MERTK (0.51) | MAPTMERTKTXNRD1GSRTDP1 | |
| SCHEMBL11198744 | 0.83 | MAPT (0.45) | MAPTMERTKTXNRD1GSRTDP1 | |
| SCHEMBL28946168 | 0.81 | MAPT (0.60) | MAPTMERTKTXNRD1GSRTDP1 | |
| SCHEMBL30574931 | 0.81 | CTSB (0.53) | MAPTMERTKTDP1L3MBTL1TSHR | |
| SCHEMBL8710611 | 0.81 | MAPT (0.53) | MAPTMERTKTXNRD1GSRTDP1 | |
| SCHEMBL30271385 | 0.81 | MAPT (0.53) | MAPTMERTKTXNRD1GSRTDP1 | |
| SCHEMBL136263 | 0.81 | CTSB (0.53) | MAPTMERTKTDP1L3MBTL1TSHR | |
| SCHEMBL6990761 | 0.81 | MAPT (0.49) | MAPTMERTKTXNRD1GSRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2095 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777015-A | Synthesis method of 3-amino-2-picolinic acid | 山西永津集团有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-113480541-B | Process for producing imidazopyridine compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-109053563-B | Method for preparing flupirtine hydrochloride | 四川青木制药有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-113480541-A | Process for producing imidazopyridine compound and intermediate thereof | 湖南化工研究院有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-112250623-A | Synthetic preparation method of 2-amino-3-nitro-4-chloropyridine | 南京麦瑞米生物技术有限公司 | 2021-01-22 | — | — | CN | claimed |
| EP-3181560-B1 | PYRIDINE AMIDOPYRIMIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | SHANGHAI ALLIST PHARMACEUTICALS CO LTD (CN) | 2020-11-25 | — | — | EP | claimed |
| CN-110218177-B | Preparation method of 2, 6-dichloro-3-nitropyridine | 新发药业有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-111662283-A | Imidazopyridine compound and intermediate, preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-110218177-A | A kind of preparation method of 2,6- dichloro-3-nitropyridine | 新发药业有限公司 | 2019-09-10 | — | — | CN | claimed |
| CN-109053563-A | A method of preparing hydrochloric acid Flupirtine | 四川青木制药有限公司 | 2018-12-21 | — | — | CN | claimed |
| US-7256295-B2 | Process for producing 2,3-diamino-6-methoxypyridine | JUBILANT ORGANOSYS LIMITED (IN) | 2007-08-14 | — | — | US | claimed |
| US-20060080790-A1 | Process for producing 2,3-diamino-6-methoxypyridine | JUBILANT ORGANOSYS LIMITED (IN) | 2006-04-20 | — | — | US | claimed |
| WO-2004108719-A9 | 2-[2-(4-MORPHOLINO)ETHYLAMINO]PYRIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM CO LTD (KR) | 2005-07-28 | — | — | WO | claimed |
| WO-2004108719-A1 | 2-[2-(4-MORPHOLINO)ETHYLAMINO]PYRIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM CO., LTD. (KR) | 2004-12-16 | — | — | WO | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-5667976-A | AMINE POLYMER COATING | BECTON DICKINSON AND COMPANY (US) | 1997-09-16 | — | — | US | claimed |
| WO-1994000600-A1 | SOLID SUPPORTS FOR NUCLEIC ACID HYBRIDIZATION ASSAYS | MICROPROBE CORPORATION (US) | 1994-01-06 | — | — | WO | claimed |
| US-4310671-A | IN THE PRESENCE OF OLEUM | OLIN CORPORATION (US) | 1982-01-12 | — | — | US | claimed |