Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225827 | 0.88 | KMT2A (0.54) | KMT2ANPC1ALDH1A1MEN1GPR88 | |
| SCHEMBL13626234 | 0.87 | GAA (0.57) | KMT2AALDH1A1MEN1GPR88POLB | |
| SCHEMBL18197284 | 0.86 | RAB9A (0.54) | KMT2ANPC1ALDH1A1MEN1GPR88 | |
| SCHEMBL13136011 | 0.86 | GPR88 (0.54) | KMT2ANPC1ALDH1A1MEN1GPR88 | |
| SCHEMBL13626320 | 0.86 | GPR88 (0.54) | KMT2ANPC1ALDH1A1MEN1GPR88 | |
| SCHEMBL6927149 | 0.85 | UGCG (0.49) | KMT2ANPC1ALDH1A1GPR88 | |
| SCHEMBL12666561 | 0.85 | NPC1 (0.49) | KMT2ANPC1ALDH1A1MEN1GPR88 | |
| SCHEMBL10434764 | 0.84 | NPC1 (0.55) | KMT2ANPC1ALDH1A1MEN1GPR88 | |
| SCHEMBL28128070 | 0.84 | NPC1 (0.55) | KMT2ANPC1ALDH1A1MEN1GPR88 | |
| SCHEMBL20238273 | 0.83 | RAB9A (0.50) | KMT2ANPC1ALDH1A1MEN1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |