Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | UGCG | Q16739 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13136011 | 1.00 | GPR88 (0.54) | GPR88LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL4148021 | 0.89 | GPR88 (0.53) | GPR88LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL22229267 | 0.89 | GPR88 (0.53) | GPR88LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL13626316 | 0.86 | KMT2A (0.53) | GPR88ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL12666562 | 0.85 | GPR88 (0.52) | GPR88LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL13626234 | 0.84 | GAA (0.57) | GPR88ALDH1A1MEN1KMT2AROCK2 | |
| SCHEMBL16938510 | 0.83 | MEN1 (0.69) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19645362 | 0.83 | MEN1 (0.69) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12091630 | 0.83 | MEN1 (0.69) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12091628 | 0.83 | MEN1 (0.69) | LMNAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |