Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626281 | 0.80 | CYP2C9 (0.40) | GAACYP2C9CYP2C19HPGDMEN1 | |
| SCHEMBL13626330 | 0.77 | PKM (0.41) | GAACYP2C9CYP2C19HPGDMEN1 | |
| SCHEMBL13626280 | 0.76 | CYP2C9 (0.39) | CYP2C9CYP2C19HPGDKMT2AMAPT | |
| SCHEMBL11694166 | 0.71 | CYP2C9 (0.44) | GAACYP2C9CYP2C19HPGDMEN1 | |
| SCHEMBL18677833 | 0.69 | HPGD (0.40) | GAACYP2C9CYP2C19HPGDMEN1 | |
| Bethanidine SCHEMBL34433 | 0.67 | ALOX12 (0.48) | GAAHPGDMEN1KMT2ASMN1; SMN2 | |
| Bethanidine SCHEMBL34434 | 0.67 | ALOX12 (0.48) | GAAHPGDMEN1KMT2ASMN1; SMN2 | |
| Bethanidine SCHEMBL34432 | 0.67 | ALOX12 (0.48) | GAAHPGDMEN1KMT2ASMN1; SMN2 | |
| Bethanidine SCHEMBL11505129 | 0.66 | MAPT (0.50) | GAAHPGDMEN1KMT2ASMN1; SMN2 | |
| Bethanidine SCHEMBL122033 | 0.64 | KMT2A (0.43) | GAAHPGDMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |