Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626281 | 0.82 | CYP2C9 (0.40) | CYP2C9CYP2C19KMT2AHPGDL3MBTL1 | |
| SCHEMBL13626330 | 0.79 | PKM (0.41) | CYP2C9CYP2C19KMT2AHPGDALDH1A1 | |
| SCHEMBL13626329 | 0.76 | GAA (0.37) | CYP2C9CYP2C19KMT2AHPGDALDH1A1 | |
| SCHEMBL10789276 | 0.67 | KMT2A (0.50) | NPC1RAB9AKMT2AHPGDTSHR | |
| SCHEMBL5108159 | 0.64 | NPC1 (0.69) | NPC1RAB9AKMT2AHPGDHTT | |
| SCHEMBL1817029 | 0.64 | ALDH1A1 (0.45) | CYP2C9CYP2C19KMT2AHPGDTSHR | |
| SCHEMBL4014042 | 0.64 | ALOX12 (0.52) | CYP2C9CYP2C19KMT2AHPGDALDH1A1 | |
| SCHEMBL599832 | 0.63 | CYP2C9 (0.67) | CYP2C9CYP2C19NPC1RAB9AKMT2A | |
| SCHEMBL3757985 | 0.63 | CYP2C9 (0.60) | CYP2C9CYP2C19NPC1RAB9AKMT2A | |
| SCHEMBL18677833 | 0.63 | HPGD (0.40) | CYP2C9CYP2C19RAB9AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |