Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 2/20 | 0.46 |
| ▸ | TK1 | P04183 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HINT1 | P49773 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116166 | 1.00 | ADORA3 (0.47) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL16258667 | 1.00 | ADORA3 (0.47) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL18537395 | 1.00 | ADORA3 (0.47) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL18537401 | 1.00 | ADORA3 (0.47) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL14620703 | 1.00 | ADORA3 (0.47) | ADORA3PNPTK1BLMUSP2 | |
| Hydrochloric Acid SCHEMBL5972616 | 0.99 | ADORA3 (0.46) | ADORA3PNPTK1BLMUSP2 | |
| Water SCHEMBL28222138 | 0.99 | ADORA3 (0.46) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL27523643 | 0.93 | TK1 (0.47) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL3779345 | 0.93 | ADORA3 (0.46) | ADORA3PNPTK1BLMUSP2 | |
| Triphosphate SCHEMBL28238456 | 0.92 | PNP (0.49) | ADORA3PNPHPGDNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280086-A1 | METHODS AND COMPOSITIONS FOR TREATING HEPATITIS C VIRUS | IDENIX PHARMACEUTICALS LLC | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280086-A1 | METHODS AND COMPOSITIONS FOR TREATING HEPATITIS C VIRUS | HAVCR2, HCCS, PYGL | ADORA3 482/4885PNP 13/4885TK1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.