Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666624 | 0.81 | ALDH1A1 (0.43) | HPGDPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9055150 | 0.79 | HPGD (0.89) | HPGDPOLBHTTKDM4CNPC1 | |
| SCHEMBL28137996 | 0.79 | PTPN1 (0.53) | HPGDPOLBHTTNPC1RAB9A | |
| SCHEMBL2908808 | 0.78 | HPGD (0.79) | HPGDPOLBHTTKDM4CNPC1 | |
| N-O-Tolylbenzamide SCHEMBL3223289 | 0.78 | HPGD (1.00) | HPGDPOLBHTTKDM4CNPC1 | |
| SCHEMBL9979656 | 0.76 | HPGD (0.59) | HPGDPOLBHTTKDM4CNPC1 | |
| SCHEMBL3690383 | 0.75 | POLB (0.79) | HPGDPOLBHTTKDM4CNPC1 | |
| SCHEMBL934859 | 0.74 | HTT (0.71) | HPGDPOLBHTTKDM4CNPC1 | |
| SCHEMBL6859613 | 0.73 | HPGD (0.77) | HPGDPOLBHTTKDM4CNPC1 | |
| SCHEMBL2732354 | 0.73 | HPGD (0.77) | HPGDPOLBHTTKDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |