Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348058 | 0.86 | ATM (0.63) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL5340269 | 0.85 | LMNA (0.43) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| Water SCHEMBL27534804 | 0.85 | LMNA (0.43) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL13848814 | 0.80 | NTRK1 (0.53) | LMNAALDH1A1HTTKDM4EMAPT | |
| SCHEMBL3690385 | 0.79 | HPGD (0.77) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL12263896 | 0.79 | ATM (0.40) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL13626445 | 0.76 | HPGD (0.63) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL5079194 | 0.75 | LMNA (1.00) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL28652342 | 0.75 | HSD17B10 (0.70) | HPGDLMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL30758600 | 0.75 | HPGD (0.70) | HPGDLMNAALDH1A1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |