Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580277 | 0.83 | KDM4E (0.56) | MAPTLMNACYP3A4HPGDCYP2C19 | |
| SCHEMBL15165560 | 0.81 | HPGD (0.65) | MAPTLMNAHPGDALDH1A1TP53 | |
| SCHEMBL2914620 | 0.80 | KCNK3 (0.68) | KCNK3KCNK9MAPTLMNACYP1A2 | |
| SCHEMBL528445 | 0.80 | KCNK3 (0.77) | KCNK3KCNK9MAPTLMNACYP1A2 | |
| SCHEMBL4783765 | 0.78 | SMN1; SMN2 (0.54) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL12666627 | 0.78 | ALDH1A1 (0.44) | MAPTHPGDALDH1A1TP53L3MBTL1 | |
| SCHEMBL27616908 | 0.77 | KCNK3 (0.68) | KCNK3KCNK9MAPTLMNACYP1A2 | |
| SCHEMBL6954756 | 0.75 | PTPN1 (0.58) | KCNK3KCNK9MAPTHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL31228747 | 0.75 | PTPN1 (0.58) | KCNK3KCNK9MAPTHPGDALDH1A1 | |
| SCHEMBL2309216 | 0.75 | MAPT (0.63) | KCNK3KCNK9MAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |