Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 1.00 |
| ▸ | EPAS1 | Q99814 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 0.79 |
| ▸ | NPC1 | O15118 | 7/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | STAT3 | P40763 | 1/20 | 0.69 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.69 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.69 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.69 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769811 | 0.89 | RAB9A (0.83) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| SCHEMBL21024443 | 0.88 | RAB9A (1.00) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| SCHEMBL28648364 | 0.88 | RAB9A (1.00) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| SCHEMBL14409565 | 0.87 | RAB9A (0.79) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL31072329 | 0.87 | RAB9A (0.97) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL31072327 | 0.87 | RAB9A (0.97) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL31072328 | 0.87 | RAB9A (0.97) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| SCHEMBL16085545 | 0.85 | SMN1; SMN2 (0.79) | HIF1AEPAS1RAB9ANPC1LMNA | |
| SCHEMBL10238341 | 0.84 | HIF1A (0.71) | HIF1AEPAS1RAB9ANPC1MAPK1 | |
| SCHEMBL24024131 | 0.84 | RAB9A (0.91) | HIF1AEPAS1RAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10548911-B2 | Small molecule anti-scarring agents | UNIVERSITY OF ROCHESTER (US) | 2020-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10548911-B2 | Small molecule anti-scarring agents | COLGALT1, MMP1, FIBP | HIF1A 3320/4885EPAS1 2164/4885RAB9A 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.