Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.41 |
| ▸ | CENPE | Q02224 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13161551 | 0.96 | DHODH (0.45) | DHODHCENPETAS1R3TAS1R1 | |
| SCHEMBL3460995 | 0.96 | DHODH (0.45) | DHODHCENPETAS1R3TAS1R1 | |
| SCHEMBL13161477 | 0.94 | CENPE (0.42) | DHODHCENPETAS1R3TAS1R1KIFC1 | |
| SCHEMBL3462063 | 0.94 | CENPE (0.42) | DHODHCENPETAS1R3TAS1R1KIFC1 | |
| SCHEMBL3462436 | 0.86 | CENPE (0.38) | DHODHCENPETAS1R3TAS1R1 | |
| SCHEMBL13161764 | 0.86 | CENPE (0.38) | DHODHCENPETAS1R3TAS1R1 | |
| SCHEMBL13625028 | 0.86 | CENPE (0.46) | DHODHCENPETAS1R3TAS1R1KIFC1 | |
| SCHEMBL3461182 | 0.86 | DHODH (0.46) | DHODHCENPETAS1R3TAS1R1KIFC1 | |
| SCHEMBL13161874 | 0.86 | DHODH (0.46) | DHODHCENPETAS1R3TAS1R1KIFC1 | |
| SCHEMBL361222 | 0.86 | CENPE (0.46) | DHODHCENPETAS1R3TAS1R1KIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286841-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. | 2009-11-19 | — | — | US | disclosed |
| US-20090286841-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286841-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | DHODH 1141/4885CENPE 54/4885TAS1R3 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.