Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034692 | 0.92 | TP53 (0.47) | TP53POLBALDH1A1THRBRXFP1 | |
| SCHEMBL1034693 | 0.92 | TP53 (0.47) | TP53POLBALDH1A1THRBRXFP1 | |
| SCHEMBL1034276 | 0.85 | THRB (0.58) | TP53POLBALDH1A1THRBRXFP1 | |
| SCHEMBL13627127 | 0.81 | PLG (0.45) | RXFP1PLGPLAUPLATTRPV3 | |
| SCHEMBL1034348 | 0.79 | EPHX2 (0.52) | TP53POLBRXFP1GAAMAP4K4 | |
| SCHEMBL1034793 | 0.78 | ALDH1A1 (0.48) | TP53ALDH1A1RXFP1GAAPLG | |
| SCHEMBL1035268 | 0.78 | GPR52 (0.44) | ALDH1A1GAATRPV3GPR52MAPT | |
| SCHEMBL1035266 | 0.78 | GPR52 (0.44) | ALDH1A1GAATRPV3GPR52MAPT | |
| SCHEMBL1035575 | 0.76 | RXFP1 (0.44) | RXFP1PLGPLAUPLATMAPT | |
| SCHEMBL1032642 | 0.76 | RXFP1 (0.44) | RXFP1PLGPLAUPLATMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134973-A1 | QUENOLINES AND RELATED ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |