Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472029 | 1.00 | BPTF (0.33) | BPTFOPRM1OPRD1OPRK1APP | |
| SCHEMBL4482834 | 0.85 | BRAF (0.34) | BPTFOPRM1OPRD1OPRK1APP | |
| SCHEMBL13627342 | 0.85 | BRAF (0.34) | BPTFOPRM1OPRD1OPRK1APP | |
| SCHEMBL4492625 | 0.84 | CHRNB2 (0.40) | OPRM1OPRD1OPRK1HPGDCHRNB4 | |
| SCHEMBL13627337 | 0.84 | CHRNB2 (0.40) | OPRM1OPRD1OPRK1HPGDCHRNB4 | |
| SCHEMBL13627331 | 0.83 | HTR2A (0.35) | NPSR1 | |
| SCHEMBL4472375 | 0.83 | HTR2A (0.35) | NPSR1 | |
| SCHEMBL4472041 | 0.83 | HTR2A (0.35) | NPSR1 | |
| SCHEMBL4489439 | 0.80 | HTR2C (0.38) | — | |
| SCHEMBL13627333 | 0.80 | HTR2C (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618980-B2 | Pyrrolo(oxo)quinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-17 | — | — | US | disclosed |