Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692361 | 0.83 | KDM4E (0.55) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL2199077 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL3061979 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL7997890 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL28411840 | 0.74 | GCGR (0.51) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL7500235 | 0.73 | LMNA (0.54) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL7471868 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL12509797 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL3979153 | 0.72 | GCGR (0.65) | ALDH1A1KMT2AMEN1HSD17B10HPGD | |
| SCHEMBL6268999 | 0.72 | MEN1 (0.51) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612092-B2 | Urea derivatives containing aromatic or heteroaromatic rings; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |