Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627860 | 0.77 | ALDH1A1 (0.50) | EPHX2ALDH1A1EPHX1KDM5A | |
| SCHEMBL13451773 | 0.76 | EPHX2 (0.43) | EPHX2EPHX1KDM5A | |
| SCHEMBL13451441 | 0.76 | EPHX2 (0.43) | EPHX2EPHX1KDM5A | |
| SCHEMBL17557791 | 0.75 | EPHX2 (0.50) | EPHX2NAMPTCYP2C9ALDH1A1EPHX1 | |
| SCHEMBL2016955 | 0.75 | EPHX1 (0.68) | EPHX2CYP2C9ALDH1A1EPHX1 | |
| SCHEMBL16418439 | 0.74 | CTSK (0.42) | EPHX2CYP2C9ALDH1A1EPHX1KDM5A | |
| SCHEMBL584795 | 0.74 | GNAI3 (0.50) | NAMPTCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL4760808 | 0.74 | CTSK (0.50) | EPHX2NAMPTCYP2C9ALDH1A1EPHX1 | |
| SCHEMBL4760751 | 0.74 | CTSK (0.50) | EPHX2NAMPTCYP2C9ALDH1A1EPHX1 | |
| SCHEMBL22900061 | 0.73 | EPHX2 (0.46) | EPHX2ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |