TAS2R16

Taste receptor type 2 member 16 · Q9NYV7 · TAS2R16 on Sugi Atlas →

468 patent compounds predicted against TAS2R16, 398 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Isoproterenol (SCHEMBL4165)	1.00	1/20
Isoproterenol (SCHEMBL4166)	1.00	1/20
Levisoprenaline (SCHEMBL250806)	1.00	1/20
Isoproterenol (SCHEMBL3253794)	1.00	1/20
Isoproterenol (SCHEMBL29386243)	1.00	1/20
Isoproterenol (SCHEMBL29519146)	1.00	1/20
Levisoprenaline (SCHEMBL29620666)	1.00	1/20
Isoproterenol (SCHEMBL7627)	0.97	1/20
Isoproterenol (SCHEMBL1333049)	0.97	1/20
Isoproterenol (SCHEMBL3672791)	0.97	1/20
Levisoprenaline (SCHEMBL4745572)	0.97	1/20
Isoproterenol (SCHEMBL5682030)	0.97	1/20
Isoproterenol (SCHEMBL6151626)	0.97	1/20
Isoproterenol (SCHEMBL9614622)	0.97	1/20
Isoproterenol (SCHEMBL28872988)	0.97	1/20
Isoproterenol (SCHEMBL3669257)	0.93	1/20
Isoproterenol (SCHEMBL28121226)	0.90	1/20
Isoproterenol (SCHEMBL2232971)	0.88	1/20
Isoproterenol (SCHEMBL28106224)	0.88	1/20
Isoproterenol (SCHEMBL28296538)	0.88	1/20

Clinical trials — most relevant to TAS2R16 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients	PHASE3	COMPLETED
Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes	PHASE2	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides	PHASE1	COMPLETED
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults	nan	COMPLETED
Flavour Programming: Fruit and Vegetable Palatability	nan	COMPLETED
Fructose and Glucose and TAS1R2 in Type 1 Diabetes	nan	COMPLETED
Sensory Study: Taste and Tongue Biology	nan	COMPLETED
Allele-specific Expression of a Bitter Taste Receptor	nan	COMPLETED
NUTRACORE, Glycaemic Index and Appetite	nan	COMPLETED
Ibuprofen Inhibits Human Sweet Taste	nan	COMPLETED
Genetic Variability in Taste Perception	nan	COMPLETED
The Effect of Lactisole on the Responses to Glucose Solution	nan	UNKNOWN
Bitter Taste Receptors in Oropharynx Cancer	nan	UNKNOWN
Sucralose and Lactisole Additions to OGTT in Humans	nan	COMPLETED
Astringency and Oral Health	nan	COMPLETED
Study of Taste Deficits	nan	COMPLETED
Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults	nan	COMPLETED
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste	nan	COMPLETED
A Study of the Function of Hormones Present In Taste Buds	nan	COMPLETED
Factors Affecting Salt Intake in Young Adults	nan	UNKNOWN
CD36 and Human Fat Taste Perception	nan	COMPLETED
The Effect of Artificial Sweeteners on Blood Glucose Response	nan	WITHDRAWN
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents	nan	NOT_YET_RECRUITING
The Obese Taste Bud Study	nan	UNKNOWN
Gustatory Dysfunction Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy	nan	COMPLETED
Impacts of Sugar-Sweetened Beverage on Body Weight	nan	COMPLETED
Physiological and Eating-behavioral Responses to Viewing Sensory-specific Food Pictures	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TAS2R16 binder may also engage these)

Protein	Name	Similarity
Q646B3	—	1.000	Q646B3 →
Q645U1	—	1.000	Q645U1 →
Q645Y4	—	1.000	Q645Y4 →
Q646D1	—	1.000	Q646D1 →
Q646E7	—	1.000	Q646E7 →
Q9JKU0	—	0.998	Q9JKU0 →
P59529	—	0.995	P59529 →
Q67ES3	—	0.995	Q67ES3 →
Q646A4	—	0.994	Q646A4 →
Q7TQB9	—	0.994	Q7TQB9 →
Q646B2	—	0.994	Q646B2 →
TAS2R60	Taste receptor type 2 member 60	0.993	landscape →
TAS2R39	Taste receptor type 2 member 39	0.993	landscape →
Q7TQA6	—	0.992	Q7TQA6 →
Q645Y8	—	0.992	Q645Y8 →
Q7TQB0	—	0.992	Q7TQB0 →
Q646B1	—	0.992	Q646B1 →
Q67ET2	—	0.992	Q67ET2 →
Q646A5	—	0.992	Q646A5 →
Q646D0	—	0.992	Q646D0 →
Q697L5	—	0.991	Q697L5 →
Q645Y9	—	0.991	Q645Y9 →
TAS2R38	Taste receptor type 2 member 38	0.991	landscape →
Q645Y7	—	0.991	Q645Y7 →
Q646F0	—	0.991	Q646F0 →
Q697L6	—	0.991	Q697L6 →
TAS2R1	Taste receptor type 2 member 1	0.991	landscape →
Q645Z1	—	0.991	Q645Z1 →
Q646C8	—	0.991	Q646C8 →
Q67ES2	—	0.990	Q67ES2 →