Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.36 |
| ▸ | CCR1 | P32246 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628658 | 0.82 | KMT2A (0.38) | CCR1ALDH1A1TSHRKMT2A | |
| SCHEMBL13628365 | 0.82 | CCR1 (0.47) | CCR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13627651 | 0.76 | CCR2 (0.39) | — | |
| SCHEMBL13627814 | 0.75 | PPARG (0.41) | DPP7CCR1DPP4L3MBTL1MEN1 | |
| SCHEMBL3326370 | 0.73 | HDAC4 (0.47) | TRPV6HDAC4OPRM1OPRD1OPRK1 | |
| SCHEMBL4808712 | 0.72 | HDAC4 (0.43) | CCR1PDK2TRPV6HDAC4ALDH1A1 | |
| SCHEMBL3326302 | 0.70 | PDK2 (0.50) | PDK2HDAC4TSHROPRD1OPRK1 | |
| SCHEMBL14011034 | 0.69 | CCR2 (0.43) | TRPV6 | |
| SCHEMBL3326090 | 0.69 | CCR2 (0.43) | TRPV6 | |
| Hydrochloric Acid SCHEMBL4146036 | 0.69 | CCR2 (0.42) | TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |