Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627810 | 0.86 | CCR1 (0.46) | KMT2AMAPK1SYKCCR1ATM | |
| SCHEMBL13628368 | 0.82 | DPP7 (0.36) | KMT2ACCR1TSHRALDH1A1 | |
| SCHEMBL13627655 | 0.78 | PDK4 (0.42) | KMT2AMAPK1SYKCCR1SCN9A | |
| SCHEMBL13627651 | 0.77 | CCR2 (0.39) | — | |
| SCHEMBL3326302 | 0.74 | PDK2 (0.50) | KMT2ASYKATMALOX15TSHR | |
| SCHEMBL13628370 | 0.73 | NPC1 (0.44) | KMT2AMAPK1SYKCCR1POLB | |
| SCHEMBL13334973 | 0.70 | CCR2 (0.43) | — | |
| SCHEMBL13361946 | 0.70 | CCR2 (0.43) | — | |
| SCHEMBL3826834 | 0.69 | PDK2 (0.45) | MAPK1SYKATMALOX15TSHR | |
| SCHEMBL13627676 | 0.68 | CDK9 (0.37) | SYKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |